under construction

  • Collection name: Center for Culture Collections of Microorganisms
  • Acronym: KUKENS
  • WDCM number: 101
  • Institution: Istanbul University
  • Address:
    Istanbul University
    Faculty of Medicine,
    Center for Culture Collections of Microorganisms (KUKENS)
    Millet Street
    Temel Bilimler Binası,
    Çapa, Fatih,
    34093 İstanbul
    Turkey
  • Website:
    Website of the catalogue or database of the collection:
  • Correspondence data:
    E-mail: zaktas@istanbul.edu.tr
    Tel.: 00902124142000-31977-32279
    Correspondent: Prof. Dr. Zerrin Aktas

Member holdings

Group(s) of biological resources stored in the collection: bacteria, yeasts, filamentous fungi, plasmids (including plasmid bearing strains), bacterial genomic DNA, phage genomic DNA, plasmid genomic DNA, resistance genes

Services offered

  • The main goals of KUKENS are to keep medically important micoorganisms and to maintain genetically standart cultures of microorganisms used to manufacture of industriel products used in the manufacture of industriel products and natural fertilizers and used in investigation in the fields of human medicine and veterinary medicine, chemistry, biochemistry, biology, genetics and industriel microbiology
  • To promote research and investigation on Culture Collections of microorganisms and Applied Microbiology
  • To organize courses, seminars, lectures and other kinds o training program to promote further training of staff working in relevant fiels in public and private institution or organizations
  • To follow relevant activities within the country and abroad, to establish contact and collabration with other intitutions for educational and research purposes and to organize and contribute to international meetings and congress on the subject of Culture collections and Apllied Microbiology
  • To promote and contribute to the establishment of new culture collection centers in Turkey and to enrich the national culture collection of microorganisms
  • To supply public and private institutions with cultures of microorganisms and to be of help in their work and/or research programs.
  • And to publish in accordance with the above and goals.
  • Identification and collection of gram positive cocci
  • Identification and collection of gram positive rods
  • Identification and collection of gram negative cocci and rods
  • Identification and collection of yeast and molds
  • Identification of plasmids and typing (new units)
  • Identification of phages and typing (new units)
  • Research

  • Molecular analysis of microorganisms found at the microorganism and Cultural Research Application Center (KUKENS)
  • Efficacy of age matched fecal microbiota transplantation in children with inflammatory bowel disease
  • Investigation of microorganisms that may be causative in cerebrospinal fluids sent from various clinics with new generation sequencing methods and microbiota analysis
  • Investigation of bacteriophage activity in Klebsiella pneumoniae strains resistant to carbapenems or pundrug.
  • Gene editing of glycopeptide resistance using the CRISPRCAS system in clinical isolates of vancomycin-resistant Enterococcus faecium.
  • Gene editing with the CRISPRCAS system in multiple resistant Klebsiella pneumoniae isolates isolated from clinical specimens.
  • Determınatıon of resıstance genes in carbapeneme-resıstant Klebsıella Pneumonıae straıns and PcrBased replıcon typıng of resıstance plasmids
  • Plasmid typing and gene regulation in multi-resistant Klebsiella pneumoniae isolates.
  • Staphylococcus aureus and Acinetobacter baumannii bacteriophage typing and evaluation of efficacy using the Galleria mellonella infection model.
  • Effect of microbiotas in hodgkin lymphoma and non-hodgkin lymphoma disease, interaction with Il-17-Il-12.
  • The role of gut microbiota in the pathogenesis and progression of multiple myeloma.
  • Mucilage problem in the Sea of Marmara (Mustafa Oral Öncül, Zerrin Aktaş. Potential Clinical Hazards of Pathogenic Microorganisms in Mucilage. DOI :10.26650/B/LS32.2023.003.02)